Solid Eye Drops: Ocular Drug Delivery Rethought

Solid Eye Drops: Ocular Drug Delivery Rethought

We are currently seeking partners for:

-Collaborative development

-Technology licensing or assignment

For Contact:

Technology Transfer:
INNOVECTIS GmbH
Altenhöferallee 5
60438 Frankfurt am Main, Germany
Phone: +49 69 25 61 632-0
 matthias.goetz@innovectis.de

Technology

Solid eye drops are an electrospun nanofiber-based drug delivery platform designed to improve ophthalmic treatment.

The water-free fiber matrix can encapsulate a wide range of drug compounds, including small molecules, antibodies and mRNA, and dissolves on the eye to form a gel that releases the active ingredient.

Applications

-The technology is suitable for ophthalmic drug delivery across a broad range of clinically relevant eye diseases.

-It is especially relevant where longer drug contact time, reduced excipients and more reliable dosing can improve treatment performance compared with conventional liquid eye drops.

Technology stage

-The platform has completed a very successful preclinical phase, and its biocompatibility was demonstrated in an OECD 492 in vitro cornea model.

–Further clinical development is ongoing, with strong results in cell viability, barrier properties and morphology compared with conventional liquid eye drops.

Patents

-The technology is covered by EP21181716, filed on 25 June 2021.

“IN-SITU DISSOLVING ELECTROSPUN POLYMER FIBERS FOR OCULAR DRUG DELIVERY”